New Nature Communications Publication by Mann & Theis Groups Harnesses the Benefits of Large-scale Peptide Collisional Cross Section (CCS) Measurements and Deep Learning for 4D Proteomics
Measured more than a million collision cross sections (CCS) from whole-proteome digests of five organisms with trapped ion mobility spectrometry (TIMS) and parallel accumulation-serial fragmentation (PASEF) on several timsTOF Pro systems Large-scale CCS data from 360 LC-TIMS-MS/MS runs, processed with MaxQuant With CCS alignment, across 347,885 peptide CCS values measured in duplicate, the median coefficient... Read more