BERGISCH GLADBACH, July 21, 2016 – The new MACSxpress® Treg Isolation Kit, human from Miltenyi Biotec facilitates both the fast and efficient isolation of regulatory T (Treg) cells from a maximum of 30 ml of fresh, anticoagulated whole blood. The MACSxpress Technique makes it possible to isolate Treg cell populations without using density gradient centrifugation and with only one labeling step. Subsequently, the cells are immediately available for further analysis or cell cultivation.
Treg cells play an important role in regulating the immune response and peripheral tolerance mechanisms. In their role as the regulators of self-tolerance in the immune system, they prevent the onset of autoimmune diseases. However, they often suppress desired reactions, such as a successful anti-tumor immune response, too. Their involvement in these immune mechanisms makes Treg cells particularly interesting for translational research.
Quick, efficient and practical: The isolation of Treg cells with MACSxpress®-Technology
Miltenyi Biotec has developed a fast process for isolating cells from whole blood – MACSxpress®-Technology. The MACSxpress Treg Isolation Kit, human, enables the extremely efficient isolation of CD4+CD25+CD127dim/- Treg cells in only two steps. In the first step CD4-negative cells are removed using the immunomagnetic MACSxpress Beads while erythrocytes are simultaneously sedimented. In the second step magnetic enrichment of CD25+ Treg cells is carried out using a MACS® Column. The marked Treg cells are held back in the column to be eluted and are then immediately available for cell cultivation or biochemical, physiological, pharmacological and morphological investigation.
For further information see the product page.
About Miltenyi Biotec
Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. The company’s innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Miltenyi Biotec’s technologies cover techniques of sample preparation, cell isolation, cell sorting, flow cytometry, cell culture, molecular analysis, and preclinical imaging. Their more than 25 years of expertise spans research areas including immunology, stem cell biology, neuroscience, and cancer, and clinical research areas like hematology, graft engineering, and apheresis. In their commitment to the scientific community, Miltenyi Biotec also offers comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has more than 1,600 employees in 25 countries – all dedicated to helping researchers and clinicians around the world make a greater impact on science and health.
###
Miltenyi Biotec Media Contact
Dr. Anja Kohmann
Communications Manager
Anja.Kohmann@miltenyibiotec.de