Research for creating substances with advanced functions utilizing microorganisms and cells, rather than chemical synthesis, has expanded in recent years in a variety of fields, including biofuels, pharmaceuticals, and food products for example. Advancement in gene editing techniques is further creating new avenues of research. In this direction of research, the effect of incorporating genes into microorganisms and cells is measured as changes in the concentrations of metabolites and metabolic enzymes. This pack significantly increases the efficiency of data analysis for these measurements.
This pack is available on the, Garuda Platform, an open, community-driven, connectivity and automation platform to connect, discover and navigate through various analytics tools, services and database (called gadgets on Garuda). The community version of the platform is available on the Garuda Alliance, and has been in operation since 2010, led by the Systems Biology Institute (SBI), a non-profit private research institution based in Tokyo. It provides an open platform to enable researchers to create a user defined workflow (called Garuda recipes), from data acquisition to data analysis, powered by an ever-increasing suite of inter-operable gadgets. Currently, the community version of the platform is in beta with more than 50 tools (gadgets) available freely, developed by the world’s leading research agencies, along with customized gadgets available in commercial versions for specific businesses and organizations.
The Shimadzu multi-omics data analysis pack presents a collection of multiple gadgets that can be interfaced with existing gadgets on the community version, creating a seamless user experience for complex data analysis and visualization workflows. This pack can be downloaded free of charge from a dedicated site on Garuda Alliance website (link available in later section). In the words of Dr. Hiroaki Kitano, President of SBI, “Connecting mass spectrometers directly with a variety of data analysis software programs developed by the world’s top research agencies in the life science field is groundbreaking. This offers the possibility of stimulating a new research cycle.”
This pack is one of the outcomes of collaborative research being pursued by Shimadzu with SBI and Osaka University, utilizing the Osaka University and Shimadzu Analytical Innovation Research Laboratory, an open innovation laboratory established by Shimadzu at Osaka University in December 2014. Fumio Matsuda, an associate professor with the Osaka University Graduate School of Information Science and Technology, developed an optimal workflow for research by combining multiple gadgets with this pack. In his words, “This pack simplified the visualization of metabolic measurement data, a conventionally tedious and time consuming process. This improves the datability*4 of extracting useful information and knowledge from big data sets obtained from mass spectrometers. Increasing the productivity of research sites enables researchers to focus on interpreting the analysis results, leading to new valuables discoveries and creations.”
In the words of Shuzo Maruyama, General Manager of the Analytical & Measuring Instruments Division at Shimadzu, “Development of life science research is progressing at rapid pace. We are no longer in an era when a single company can assess cutting edge needs and provide the solutions. We will work continuously with global research agencies in order to keep providing solutions to respond to potential user needs.”